New as of Sept. 2002

Aangamik® Gluta-DMG™

by FoodScience of Vermont

Enhances oxygen utilization
Increases antioxidant activity
Improves athletic performance and recovery
Increases intracellular glutathione production
Enhances immune defense

Gluta-DMG is a synergistic combination of two nutritional products, an undenatured whey protein isolate and Dimethylglycine (DMG).

The special whey protein isolate represents proprietary technology. It contains sub-families of bioactive proteins, such as lactoferrin, alpha-lactoalbumin and serum albumin, which have high levels of glutathione precursors (building blocks) as compared to other whey proteins and casein. It is efficacious for immune system function and for producing a sustained cellular increase of glutathione.

Dimethylglycine (DMG) is a naturally occurring intermediary metabolite produced from choline and found in small levels in grains, seeds, and in liver. As a dietary supplement, it supports circulatory, cardiovascular, neurological, and immune functions as well as muscle recovery and endurance. The human body produces DMG in very small amounts. Supplementing the diet with higher levels of DMG greatly improves the nutritional environment of the cell. Dimethylglycine has been found effective in supporting immune system function and better utilization of oxygen at the cellular level. Several U.S. patents have been issued for N, N-Dimethylglycine's value and use in improving immunity and for benefiting cellular processes. DMG reduces lactic acid build up in the muscle, thereby shortening recovery time after strenuous exercise and improving endurance.

Research on the Special Whey Protein Isolate
Carefully controlled scientific studies performed since 1976 on this special whey protein isolate, a by-product of the cheese industry, have shown a 30% longer life span (in tests with mice), antioxidant support, and a greater immune response upon foreign antigen challenge.

These benefits of the specially prepared whey protein isolate have been shown to be linked to its ability to increase the intracellular synthesis of glutathione (GSH), the master antioxidant and detoxifier found in all mammalian cells.

On the Chemistry of Intracellular Glutathione
Studies have shown that feeding glutathione or its precursor, cysteine, do not boost cellular glutathione levels. This is because of the instability of cysteine in the blood (it readily oxidizes to cystine) and because glutathione apparently cannot be transported intact across the cell membrane. The whey protein isolate contains the dipeptide gamma-glutamylcysteine—which is absorbed intact into the cell. The key limitation to the production of glutathione within the cell is the reaction that combines cysteine with glutamic acid to make gamma-glutamylcysteine. Since the special whey protein isolate directly provides the cell with a high level of gamma-glutamylcysteine, this rate limiting step is bypassed. The gamma-glutamylcysteine then reacts with glycine to produce glutathione.